KHK-IN-1 itoren (Pivoxil) CC(=O)NC1=CC=CC=C1C(=O)O[C@]12CN(CC)C3[C@@H]4C[C@H]1[C@@]3([C@H](CC2)OC)[C@@H]1C[C@H]2[C@H](OC)[C@]1(O)[C@]4(O)C[C@@H]2OC

CC(=O)NC1=CC=CC=C1C(=O)O[C@]12CN(CC)C3[C@@H]4C[C@H]1[C@@]3([C@H](CC2)OC)[C@@H]1C[C@H]2[C@H](OC)[C@]1(O)[C@]4(O)C[C@@H]2OC

Smiles: COC1=CC2O[C@H]3OC=C[C@H]3C=2C2OC(=O)C3[C@@H](O)CCC=3C=21

KDOAM-25 citrate is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM

with antitumor property

InChi: InChI=1S/C24H16N4O2/c1-27-15-9-4-2-7-13(15)17-19-20(24(30)26-23(19)29)18-14-8-3-5-10-16(14)28(12-6-11-25)22(18)21(17)27/h2-5

KHK-IN-1 itoren (Pivoxil) CC(=O)NC1=CC=CC=C1C(=O)O[C@]12CN(CC)C3[C@@H]4C[C@H]1[C@@]3([C@H](CC2)OC)[C@@H]1C[C@H]2[C@H](OC)[C@]1(O)[C@]4(O)C[C@@H]2OCKHK IN 1 is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM; interacts with Asp 27B in the ATP binding region of KHK. Product information CAS Number: 1303469 70 6 Molecular Weight: 422. 55 Formula: C21H26N8S Chemical Name: N8 (cyclopropylmethyl) N4 [2 (methylsulfanyl)phenyl] 2 (piperazin 1 yl) [1,3]diazino[5,4 d]pyrimidine 4,8 diamine Smiles: CSC1=CC=CC=C1NC1=NC(=NC2C1=NC=NC=2NCC1CC1)N1CCNCC1 InChiKey: HFLMLZKGLUEWBU UHFFFAOYSA N InChi: