ML281 Catalog No.:M7498-2 Boceprevir (SCH 503034) has a

Boceprevir (SCH 503034) has a potency of 14 nM (Ki) average over a large number of runs

Chemical Name: 5-((1H-pyrrolo[2

for 14 weeks) results in a profound delay in tumor growth in NCR-Nu mice bearing MDA-MB-435/GFP tumor

Epub 2019 Feb 10

SMER3 was used at 10-20 µM final concentration in various in vitro assays

ML281 Catalog No.:M7498-2 Boceprevir (SCH 503034) has aML281 is a potent and selective inhibitor of Serine threonine kinase 33 (STK33) with IC50 of 0. 014 M. ML281 is selectively toxic to KRAS dependent cancer cell lines. Product information CAS Number: 1404437 62 2 Molecular Weight: 389. 47 Formula: C22H19N3O2S Chemical Name: N [2 (3,4 Dihydro 3 oxo 2 quinoxalinyl) 4 (1 methylethyl)phenyl] 2 thiophenecarboxamide Smiles: CC(C)C1=CC(C2=NC3=CC=CC=C3NC2=O)=C(C=C1)NC(=O)C1=CC=CS1 InChiKey: HWOYIOLMBQSTQS