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Villagra A
InChi: InChI=1S/C23H33N5O2/c1-2-14-27-15-17-28(18-16-27)20-8-6-19(7-9-20)21(29)26-23(10-4-3-5-11-23)22(30)25-13-12-24/h6-9H
Armaiz-Pena GN
27)23-7-9-28-10-8-23/h2-6
SF-1670 specifically binds to the active site of PTEN inhibiting its activity with an IC50 value of 2 μM
U0126-EtOH - CAS# 1173097-76-1 174 Villagra AU0126 EtOH, CAS No. 1173097 76 1, is a highly selective inhibitor of MEK1 2 with IC50 of 0. 07 M 0. 06 M, 100 fold higher affinity for N3 S218E S222D MEK than PD98059. This inhibition of MEK1 2 is noncompetitive with ERK and ATP. Product information CAS Number: 1173097 76 1 Molecular Weight: 426. 56 Formula: C20H22N6OS2 Chemical Name: bis({amino[(2 aminophenyl)sulfanyl]methylidene})butanedinitrile; ethanol Smiles: CCO.
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