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2 μM and 1
also known as IWR-1-endo
InChi: InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18
PDE6 and PDE1
which inhibits degranulation downstream of protein kinase C activation or Ca2+ influx from an internal store in RBL-213 cells
Moxonidine Catalog No.:M9133-10 2 μM and 1Moxonidine is a centrally acting antihypertensive drug that is selective agonist at the imidazoline receptor subtype 1 (I1). This receptor subtype is found in both the rostral ventro lateral pressor and ventromedial depressor areas of the medulla oblongata. Moxonidine therefore causes a decrease in sympathetic nervous system activity and a decrease in blood pressure. Moxonidine may also promote sodium excretion, improve insulin resistance and glucose