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Formula: C20H19ClN6O2
Molecular Weight: 197
Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo
InChi: InChI=1S/C42H49N7O8/c1-47(23-31-34(56-3)20-26(21-35(31)57-4)30-24-48(2)40(53)29-22-43-19-16-27(29)30)25-37(51)45-18-10-8-6-5-7-9-17-44-32-13-11-12-28-38(32)42(55)49(41(28)54)33-14-15-36(50)46-39(33)52/h11-13
20(4):91-9
Bafetinib analog, Lyn-IN-1 - CAS# 887650-05-7 clozanide Formula: C20H19ClN6O2Bafetinib, also known as INNO 406 and NS187, is an orally bioavailable 2 phenylaminopyrimidine derivative with potential antineoplastic activity. Bafetinib specifically binds to and inhibits the Bcr Abl fusion protein tyrosine kinase, an abnormal enzyme produced by Philadelphia chromosomal translocation associated with chronic myeloid leukemia (CML). This agent also inhibits the Src family member Lyn tyrosine kinase, upregulated in imatinib resistant
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