AG 18 - CAS# 118409-57-7 diine hydrochloride Smiles: COC1=CN(N=C(C1=O)C1=CC=NN1C1C=CC=CC=1)C1=CC=C(C=C1F)N1C=CC=N1

Smiles: COC1=CN(N=C(C1=O)C1=CC=NN1C1C=CC=CC=1)C1=CC=C(C=C1F)N1C=CC=N1

Smiles: CC(C)=O

also known as LP-778902

Chemical Name: 1-methyl-4-{6-thiatricyclo[8

7b-dihydroxy-3-( hydroxymethyl)-1

AG 18 - CAS# 118409-57-7 diine hydrochloride Smiles: COC1=CN(N=C(C1=O)C1=CC=NN1C1C=CC=CC=1)C1=CC=C(C=C1F)N1C=CC=N1AG 18, also known as RG 50810; RG 50858; TX 825; Tyrphostin A23; Tyrphostin AG 18. AG 18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 M in the human epidermoid carcinoma cell line A431. AG 18 inhibits internalization of the transferrin receptor by perturbing the interaction between tyrosine motifs and the medium chain subunit of the AP 2 adaptor complex. Product information CAS Number: 118409 57 7 Molecular