Intracellular delivery of 10-hydroxycamptothecin with targeted nanostructured lipid carriers against multidrug resistance
Methyltetrazine-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs
Chemical Name: (2S)-1-(hexadecanoyloxy)-3-hydroxypropan-2-yl hexadecanoate
Smiles: OC1C=C(O)C2C(=O)[C@H](CC3C=CC(O)=CC=3)COC=2C=1
24 hours) blocks TNF-induced necroptosis in a concentration-dependent manner
PROTAC ER Degrader-4 hyl apixaban sulfate sodium Intracellular delivery of 10-hydroxycamptothecin withPROTAC ER Degrader 4 is a PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0. 8 nM. PROTAC ER Degrader 4 induces ER degradation in MCF 7 cells with an IC50 of 0. 3 nM. Product information CAS Number: 2361114 15 8 Molecular Weight: 1005. 19 Formula: C53H67F3N6O8S Chemical Name: (2S,4R) 1 [(2S) 2 (2 {2 [2 (2 {3,5 difluoro 4 [(1R,3R) 2 (2 fluoro 2 methylpropyl) 3 methyl 1H,2H,3H,4H,9H pyrido[3,4 b]indol 1