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by acting downstream of eIF2α phosphorylation
HLI-373 induces apoptosis in several tumor cell lines that express wild-type p53 such as LOX-IMVI
InChiKey: CTESJDQKVOEUOY-UHFFFAOYSA-N
PubMed PMID: 15860572
The mean IC50 value of 47 nM for Narciclasine across a panel of 60 cancer cell lines[1]
Etonogestrel 63922 by acting downstream of eIF2αEtonogestrel is a steroidal progestin used in hormonal contraceptives, most notably the subdermal implant Nexplanon and the vaginal ring NuvaRing. Etonogestrel is the active metabolite of the inactive prodrug desogestrel, one of two third generation progestins found in some epidemiological studies of combined oral contraceptive pills to be associated with a higher risk of venous thrombosis than combined oral contraceptive pills containing certain