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InChi: InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6
M77976 makes hydrophobic interactions with the side chains of Asn258
Sulforaphane inhibits the reinitiation of growth and diminishes cellular viability in quiescent colon carcinoma cells (HT29) and has a lower toxicity on differentiated CaCo2 cells
Smiles: CC1NC(/C=C2/C3=CC(F)=CC=C3NC/2=O)=C(C)C=1C(=O)NCCN(CC)CC
RNA helicase DDX3: a novel therapeutic target in Ewing sarcoma
Osimertinib dimesylate 0-anthracenedione InChi: InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6Osimertinib dimesylate (AZD 9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R T790M, respectively. Product information CAS Number: 2070014 82 1 Molecular Weight: 691. 82 Formula: C30H41N7O8S2 Chemical Name: N (2 {[2 (dimethylamino)ethyl](methyl)amino} 4 methoxy 5 {[4 (1 methyl 1H indol 3 yl)pyrimidin 2 yl]amino}phenyl)prop 2 enamide; bis(methanesulfonic acid) Smiles:
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