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Formula: C20H23N10O12P2
and concomitant to the activation of AMPK signaling
Probing the cation binding modes of macrocyclic HCV protease inhibitor BILN 2061 by multinuclear NMR
InChi: InChI=1S/C30H43N7O7S/c1-20-26(45-19-33-20)22-7-5-21(6-8-22)16-32-28(40)24-15-23(38)17-37(24)29(41)27(30(2
two important members of the sirtuin family
HE-3235 5217 Formula: C20H23N10O12P2HE 3235 is a novel antagonist of androgen receptor. Androgen receptor (AR) is an adrenal hormone belongs to the steroid hormone receptor family of molecules. AR is responsible for mediating the physiologic effects of androgens by binding to specific DNA sequences that influence transcription of androgen responsive genes. Variations in the AR gene may lead to genetic predisposition to prostate cancer development and severity . In vitro: In LNCaP cells
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