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Aristolactam I Catalog No.:M12596-10 selective and cell-permeable inhibitor of

SKU: 78609492512

4.3
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Description

selective and cell-permeable inhibitor of EGFR tyrosine kinase and ErbB2

PIK-III prevents the turnover of GFP-tagged p62 under basal conditions and when autophagy is activated

in general

Smiles: C[C@@H]1O[C@H](C[C@H](N)[C@@H]1O)O[C@H]1C[C@@](O)(CC2C1=C(O)C1C(=O)C3=C(C=CC=C3C(=O)C=1C=2O)OC)/C(/CO)=N/NC(=O)CCCCCN1C(=O)C=CC1=O

TAS-301 (1-10 μM) also decreases bFGF-induced BrdU incorporation

Aristolactam I Catalog No.:M12596-10 selective and cell-permeable inhibitor ofAristololactam I (AL I), is the main metabolite of aristolochic acid I (AA I), participates in the processes that lead to renal damage. Aristololactam I (AL I) directly injures renal proximal tubule cells, the cytotoxic potency of AL I is higher than that of AA I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase 3 dependent pathway. Product information CAS Number: 13395 02 3 Molecular

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