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Formula: C24H23N7O3S
(1998) J Med Chem
1341224-83-6
gov/books/NBK154499/ PubMed PMID: 24027804
2-ef][2]benzazepin-6-one
MK-4827 Hydrochloride l blocker Formula: C24H23N7O3SNiraparib, also know as MK 4827, is an inhibitor of poly (ADP ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base excision repair (BER) pathway. Product information CAS Number: 1038915 64 8 Molecular Weight: 356. 85 Formula: