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GS441524-intermediate
PubMed Central PMCID: PMC5630333
PubMed PMID: 22574676
Treatment of nude mice bearing human ovarian and colon tumor xenografts with Belinostat (10-40 mg/kg/day i
23-bis(methoxycarbonyl)-4
IQ 1 - CAS# 331001-62-8 60423 GS441524-intermediateIQ 1, CAS No. 331001 62 8, has many functions such as decreasing Wnt stimulated phosphorylation, maintaining the pluripotency of murine ESCs, preventing PP2A Nkd interaction and so on. IQ 1 maintains the pluripotency of murine ESCs in long term culture in a Wnt dependent manner. IQ 1 decreased Wnt stimulated phosphorylation of p300 at Ser 89.IQ 1 binds to serine threonine phosphatase PP2A and prevents PP2A Nkd interaction.The binding of IQ 1 to PR72
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