![CGP 35348 Histone Methyltransferase 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-hydroxy-7-({[(methylsulfanyl)carbonyl]oxy}methyl)-1H](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M22507_1635325492.gif?v=1635325494)
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5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-hydroxy-7-({[(methylsulfanyl)carbonyl]oxy}methyl)-1H
Chemical Name: 3-[5-(aminomethyl)-1-oxo-2
Zhong Yao Cai
InChiKey: PBGMRXNTLPSDNR-UHFFFAOYSA-N
IDX184 is a second generation
CGP 35348 Histone Methyltransferase 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-hydroxy-7-({[(methylsulfanyl)carbonyl]oxy}methyl)-1HCGP 35348 is a selective antagonist of aminobutyric acidB (GABAB) receptor with IC50 value of 34 M . The GABAB receptor is a metabotropic transmembrane receptors for GABA that is linked via G protein to potassium channel. It stimulates the opening of K+ channel and hyperpolarize the neuron. CGP 35348 is a selective GABAB receptor antagonist that can penetrate the blood brain barrier. In rat cortex slices, CGP 35348 inhibited the potentiating effect of
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