PF-04995274 0270 is an aromatic guanylhydrazone compounds

is an aromatic guanylhydrazone compounds with antimalarial activity

J Steroid Biochem Mol Biol

InChiKey: LBEJYFVJIPQSNX-SOAUALDESA-N

which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K

Capromorelin Tartrate

PF-04995274 0270 is an aromatic guanylhydrazone compoundsPF 04995274 (PF 4995274) is a potent, high affinity, orally active and partial agonist of serotonin 4 receptor (5 HT4R) with EC50 of 0. 47 nM, 0. 36 nM, 0. 37 nM and 0. 26 nM for human 5 HT4A 4B 4D 4E, respectively. As for rat 5 HT4S 4L 4E, the EC50 is 0. 59 nM, 0. 65 nM and 0. 62 nM, respectively. PF 04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease. Product information CAS Number: 1331782 27 4