You don't choose a target for Eden, Seat of the Sanctum's last ability at the time you activate it
Obviously I still advocate for playing cards like Aetherize, especially if you are in mono-blue, but unless youre playing hard control a spell like Raise the Palisade is going to come in very handy
Sauron, the Lidless Eye Sauron, the Lidless Eye has a good ETB effect and a nice mana sink that can drain a lot of life from your opponents in the right circumstances
Whether you're playing pingers or goblins, you're going to want to consider adding this card to your deck
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From a mechanical perspective, this life loss drawback is reminiscent of black cards like Phyrexian Negator or Plague Spitter, but with a redemptive twist built in