MDV-3100 - CAS# 915087-33-1 238 is an activator of the

is an activator of the Wnt pathway by acting in a Wnt ligand–dependent manner

7-difluoro-N-(4-(methylamino)cyclohexyl)-N-(3-(pyridin-4-yl)benzyl)benzo[b]thiophene-2-carboxamide

(1997) J Biol Chem

Smiles: COC1C=CC(=CC=1)OC1C=C2C(=CC=1NS(=O)(=O)C1=CC(OC)=C(C=C1)OC)N(C)C(=O)N2C

PubMed Central PMCID: PMC4248330

MDV-3100 - CAS# 915087-33-1 238 is an activator of theEnzalutamide, also known as MDV3100, CAS No. 915087 33 1, is an orally bioavailable, organic, non steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. Through a mechanism that is reported to be different from other approved AR antagonists, selective androgen receptor modulator MDV3100 inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation