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Ranolazine none I NBQX (20 mg/kg

SKU: 1027927083

4.1
USD75.00 USD101.00

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Description

NBQX (20 mg/kg

specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity

The inhibition of CDC20 with its inhibitor Apcin reduces the adhesion rate and proliferation ability to RL95-2 and HEC-1A cells

InChi: InChI=1S/C42H49N7O8/c1-47(23-31-34(56-3)20-26(21-35(31)57-4)30-24-48(2)40(53)29-22-43-19-16-27(29)30)25-37(51)45-18-10-8-6-5-7-9-17-44-32-13-11-12-28-38(32)42(55)49(41(28)54)33-14-15-36(50)46-39(33)52/h11-13

2018 Jul 20

Ranolazine none I NBQX (20 mg/kgRanolazine is an anti ischemic compound, which inhibits late sodium current that results in a reduction of Na+ dependent Ca2+ overload. Studies indicate that ATP production is shifted towards glucose oxidation by Ranolazine. This is due to the fact that more oxygen is required to phosphorylate the same amount of ATP during fatty acid oxidation than carbohydrate oxidation. These studies indicate that Ranolazine also inhibits oxygen consumption and

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