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Syk-IN-3 Catalog No.:M15130-2 Smiles: CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1

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Description

Smiles: CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1

WO2015058191A1

L-Moses binds in the acetylated lysines (KAc) -binding pocket of PfGCN (blue ribbon and sticks) and makes H-bonds (dotted lines) through the triazole to N1436 and the first of a network of four water molecules (red spheres)

WHI-P154 Enhances the Chemotherapeutic Effect of Anticancer Agents in ABCG2-overexpressing Cells

Blockade of GLUT1 by WZB117 resensitizes breast cancer cells to adriamycin

Syk-IN-3 Catalog No.:M15130-2 Smiles: CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1Syk IN 3, a potent spleen tyrosine kinase (Syk) inhibitor, extracted from patent WO2011075515A1, compound example 152, has an IC50 of 1 nM. Product information CAS Number: 1312534 69 2 Molecular Weight: 452. 57 Formula: C24H28N4O3S Chemical Name: (1S,4R) 4 hydroxy 2,2 dimethyl 4 (5 {3 methyl 5 [(4 methylpyrimidin 2 yl)amino]phenyl} 1,3 thiazol 2 yl)cyclohexane 1 carboxylic acid Smiles:

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