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/levoleucovorin is the active stereoisomer/
1) GNF-6231 shows IC50s of greater than 10 μM on all CYP isoforms tested2) GNF-6231 have favorable potency and a PK profile across preclinical species upon oral administration
Smiles: CC(=O)C1C=CC(=CC=1)NC(=O)C=CC1=CC=C(CC)O1
Nicotinamide N-oxide
Smiles: O=C(N/N=C/C1C=CC(Cl)=CC=1)N1CC2=C(NC3=CC(=CC=C3)C(F)(F)F)N=CN=C2CC1
Acolbifene Size:Contact [email protected] for quotation /levoleucovorin is the active stereoisomer/Acolbifene (EM 652), the active metabolite of EM800, is an orally active pure antiestrogen and selective estrogen receptor antagonist. Acolbifene (EM 652) inhibits estradiol (E2) induced transcriptional activity of ER (IC50 = 2 nM) and ER (IC50 = 0. 4 nM). Acolbifene (EM 652) possesses potent and pure anticarcinogenic properties. Product information CAS Number: 182167 02 8 Molecular Weight: 457. 56 Formula: C29H31NO4 Chemical Name: (2S) 3 (4
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