![NSC-87877 disodium Catalog No.:M27711-C Chemical Name: N'-[(1E)-(4-oxo-4H-chromen-3-yl)methylidene]pyridine-3-carbohydrazide](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M27711_1636002671.gif?v=1636002673)
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Chemical Name: N'-[(1E)-(4-oxo-4H-chromen-3-yl)methylidene]pyridine-3-carbohydrazide
with antioestrogenic property
The pyridine regio-isomer GSK-J2 displays significantly less on-target activity (IC50 > 100 µM for human JmjD3) and thus can be used as control for target effects in vitro
7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1
and 23-fold reduction for 600 mg/kg/day
NSC-87877 disodium Catalog No.:M27711-C Chemical Name: N'-[(1E)-(4-oxo-4H-chromen-3-yl)methylidene]pyridine-3-carbohydrazideNSC 87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH PTP2 and SH PTP1), with IC50 values of 0. 318 M, 0. 355 M shp2 and shp1, respectively. NSC 87877 also inhibits dual specificity phosphatase 26 (DUSP26). Product information CAS Number: 56932 43 5 Molecular Weight: 503. 42 Formula: C19H11N3Na2O7S2 Chemical Name: disodium 8 hydroxy 7 [2 (6 sulfonatonaphthalen 2 yl)diazen 1 yl]quinoline 5 sulfonate Smiles:
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