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Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases
it induced dramatic apoptosis in above AML cells
is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro
Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1
It binds within the internal cavity of HIF-2α PAS-B (Kd of 81 nM) and disrupts heterodimerization of the full-length HIF-2 transcription factor
Cediranib Size:2mg solid Manipulation of prenylation reactions byCediranib, also known as AZD 2171, is a potent and selective VEGF inhibitor with antineoplastic activities. Competing with adenosine triphosphate, cediranib binds to and inhibits all three vascular endothelial growth factor receptor (VEGF 1, 2, 3) tyrosine kinases, thereby blocking VEGF signaling, angiogenesis, and tumor cell growth. Product information CAS Number: 288383 20 0 Molecular Weight: 450. 51 Formula: C25H27FN4O3 Synonym: AZD2171 AZD 2171
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