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Aβ42-IN-2 has an IC50 of 6
Smiles: CC1=C2[C@@H](O)[C@](C)(CO)C=C2C(=O)[C@](C)(O)C21CC2
Formula: C14H10F3NO2
Chemical Name: 5-nitro-6-[2-(propan-2-yl)benzenesulfonyl]quinolin-8-amine
4-tetrahydroquinolin-6-yl]benzoate
ONO 4817 707enbufen Aβ42-IN-2 has an IC50 ofONO 4817 is a potent inhibitor of MMP 2, MMP 3, MMP 7, MMP 9, MMP 12 and MMP 13 with IC50 value of 0. 73 nM, 42 nM, 2500 nM, 1. 1 nM, 2. 1 nM, 0. 45 nM and 1. 1 nM, respectively . Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases that belong to the metzincin superfamily and play an important role in tissue remodeling associated with various physiological or pathological processes such as morphogenesis, angiogenesis, tissue repair,
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