4-(2-Bromophenyl)-2, 6-dimethyl-3, 5-pyridinedicarboxylic Acid-d10 Diethyl Ester ipt Discovery of MD-224 as a

Discovery of MD-224 as a First-in-Class

2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol

Bioorganic & Medicinal Chemistry Letters 5(4)

albeit somewhat higher (7-fold) than that of the parent S119 against influenza A/WSN/33 H1N1 (WSN) virus

InChi: InChI=1S/C19H17Cl3N2S/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22/h1-5

4-(2-Bromophenyl)-2, 6-dimethyl-3, 5-pyridinedicarboxylic Acid-d10 Diethyl Ester ipt Discovery of MD-224 as aProduct information CAS Number: 1329793 25 0 Molecular Weight: 418. 35 Formula: C19H22BrNO4 Chemical Name: 3,5 bis[(1,1,2,2,2 H)ethyl] 4 (2 bromophenyl) 2,6 dimethyl 1,4 dihydropyridine 3,5 dicarboxylate Smiles: [2H]C([2H])([2H])C([2H])([2H])OC(=O)C1C(C(C(=O)OC([2H])([2H])C([2H])([2H])[2H])=C(C)NC=1C)C1=CC=CC=C1Br InChiKey: HHVXLILNSZSXPW JKSUIMTKSA N InChi: InChI=1S C19H22BrNO4 c1 5 24 18(22)15 11(3)21 12(4)16(19(23)25 6 2)17(15)13 9 7 8 10 14(13)20