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At 2 h after SQ delivery at 10 mg/kg the brain Cmax is 161 ng/g while dosing at 30 mg/kg orally
is shown to be an even more potent and selective inhibitor of GRK2 with an IC50 of 0
InChiKey: DKYWVDODHFEZIM-UHFFFAOYSA-N
Cell cycle analysis shows that 35% Sapacitabine-treated cells are arrested in late-S phase and 41% in G2/M phase
Formula: C26H30ClN7O2
2, 3-dihydrothieno-Thiadiazole Carboxylate Size:Contact [email protected] for quotation At 2 h after SQ2,3 dihydrothieno Thiadiazole Carboxylate is a CYP450 (CYP2E1 and CYP2B4) inhibitor. The cytochrome P450 (CYP) enzymes are a superfamily of oxidative catalysts critical in the biosynthesis and metabolism of various endobiotics such as steroids and steroid hormones, the neurotransmitter nitric oxide, and vitamins A and D. The cytochrome P450 enzymes are also involved in the metabolism of xenobiotics including natural products, drugs, and other organic