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2-4H3/q+1/t23-
ClH/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35
Passacantilli S
When currents are stimulated to a Vtest of +10 mV from a Vh of -110 mV
InChiKey: SKJLITFHSZNZMQ-SGNDLWITSA-N
TPX-0131 - CAS# 2648641-36-3 yl Carvedilol 2-4H3/q+1/t23-TPX 0131 is a potent, selective, CNS penetrant and orally active inhibitor of wild type ALK (IC50 of 1. 4 nM) and ALK resistant mutation, e. g. G1202R (IC50 of 0. 3 nM), L1196M (IC50 of 0. 3 nM). TPX 0131 has strong antitumor activities. Product information CAS Number: 2648641 36 3 Molecular Weight: 447. 41 Formula: C21H20F3N5O3 Chemical Name: (18S) 18 (difluoromethyl) 13 fluoro 7,7 dimethyl 9,20 dioxa 1,2,6,17,23 pentaazapentacyclo[19. 3. 1. 0,. 0,.
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