Tyk2-IN-7 ogladine Smiles: CC[C@@H](CO)NCCN[C@H](CO)CC

Name: Tyk2-IN-7 ogladine Smiles: CC[C@@H](CO)NCCN[C@H](CO)CC
Brand: cargainteligente.com
SKU: 13572812107
Price: 100.00 USD
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SKU: 13572812107

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Description

Smiles: CC[C@@H](CO)NCCN[C@H](CO)CC

Fabesetron (FK1052) can be used in the study for both acute and delayed emesis induced by cancer chemotherapy

InChiKey: ZTQSADJAYQOCDD-HUGMCNGHSA-N

CAS Number: 84468-24-6

Solubility: DMSO : 100 mg/mL (846

Tyk2-IN-7 ogladine Smiles: CC[C@@H](CO)NCCN[C@H](CO)CCTyk2 IN 7 (Compound 48) is a TYK2 JH2 inhibitor, binds to TYK2 JH2 domain with IC50 and Ki. app of 0. 00053 M and 0. 00007 M, respectively. Tyk2 IN 7 (Compound 48) provides a highly selective alternative to conventional TYK2 orthosteric inhibitors, inhibits TYK2 JAK1 JAK2 kinase domain. Tyk2 IN 7 (Compound 48) provides robust inhibition in a mouse IL 12 induced IFN pharmacodynamic model as well as efficacy in an IL 23 and IL 12 dependent mouse colitis

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