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66 μM for RT112 and RT4
2010 Nov 18
[Arginase inhibitor nor-NOHA induces apoptosis and inhibits invasion and migration of HepG2 cells]
which convert arachidonic acid to prostaglandin H2 (PGH2)
InChi: InChI=1S/C15H10FNO3/c1-2-8-5-10(18)7-12-14(8)20-15(17-12)9-3-4-13(19)11(16)6-9/h2-7
BAY-293 orph 66 μM for RT112 andBAY 293 selectively inhibits the KRAS SOS1 interaction with an IC50 of 21 nM. Product information CAS Number: 2244904 70 7 Molecular Weight: 448. 58 Formula: C25H28N4O2S Chemical Name: 6,7 dimethoxy 2 methyl N [1 (4 {2 [(methylamino)methyl]phenyl}thiophen 2 yl)ethyl]quinazolin 4 amine Smiles: CC1N=C(NC(C)C2=CC(=CS2)C2=CC=CC=C2CNC)C2=CC(OC)=C(C=C2N=1)OC InChiKey: WEGLOYDTDILXDA UHFFFAOYSA N InChi: InChI=1S C25H28N4O2S c1 15(24 10 18(14 32 24)19 9 7 6 8