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is a DNA methyltransferase (DNMT) inhibitor
treatment with 9 μM compound reduces viral titer by >104-fold
Icaritin treatment also significantly inhibits Bcl-2 protein expression and up-regulated Bax protein expression in K562 with a dose-dependent manner accompanied by the cleavage activation of caspase-3 or caspase-9
Wanming He
CAS Number: 283159-94-4
DSP-0565 empferol 3-O-gentiobioside is a DNA methyltransferase (DNMT)DSP 0565 (compound 17a) is a strong, broad spectrum anti epileptic drug (AED) candidate with unique GABAergic function. DSP 0565 shows anti convulsant activity in various models (scPTZ, MES, 6 Hz and amygdala kindling) with good safety margin. Product information CAS Number: 1226855 28 2 Molecular Weight: 229. 25 Formula: C14H12FNO Chemical Name: 2 {2' fluoro [1,1' biphenyl] 2 yl}acetamide Smiles: NC(=O)CC1=CC=CC=C1C1=CC=CC=C1F InChiKey:
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