H-1437 cells
14 nM) and potently degrades ERα in MCF-7 breast cancer cells (IC50 = 0
Epub 2020 Mar 10
c-Met is also known as hepatocyte growth factor receptor (HGFR)
It is marketed as Serevent in the US
FKBP12 PROTAC RC32 tidine chloride H-1437 cellsFKBP12 PROTAC RC32 (RC32) is a potent FKBP12 degrader based on PROTAC technology. FKBP12 PROTAC RC32 contains conjugation of Rapamycin (HY 10219) and a ligand for an E3 ubiquitin ligase (Pomalidomide; HY 10984). Product information CAS Number: 2375555 66 9 Molecular Weight: 1426. 69 Formula: C75H107N7O20 Chemical Name: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R) 12 [(2R) 1 [(1S,3R,4R) 4 {2 [(1 {2 [2 (2 {[2 (2,6 dioxopiperidin 3 yl) 1,3