TC-N 22A Catalog No.:M18602-C Smiles: [2H]C1([2H])C([2H])([2H])C([2H])([2H])N(C2CCN(CC2)C(=O)OC2C=C3C(CC)=C4CN5C(=CC6=C(COC(=O)[C@]6(O)CC)C5=O)C4=NC3=CC=2)C([2H])([2H])C1([2H])[2H]

Smiles: [2H]C1([2H])C([2H])([2H])C([2H])([2H])N(C2CCN(CC2)C(=O)OC2C=C3C(CC)=C4CN5C(=CC6=C(COC(=O)[C@]6(O)CC)C5=O)C4=NC3=CC=2)C([2H])([2H])C1([2H])[2H]

reveals EC50 value of 0

CBL0137 hydrochloride is an inhibitor of the histone chaperone

4-benzoxazepin-7-yl]pyridin-2-amine

CWHM-1552 is an orally efficacious inhibitor of P

TC-N 22A Catalog No.:M18602-C Smiles: [2H]C1([2H])C([2H])([2H])C([2H])([2H])N(C2CCN(CC2)C(=O)OC2C=C3C(CC)=C4CN5C(=CC6=C(COC(=O)[C@]6(O)CC)C5=O)C4=NC3=CC=2)C([2H])([2H])C1([2H])[2H]TC N 22A is a potent, selective, orally active and brain permeable mGlu4 PAM with an EC50 of 9 nM in human mGlu4 expressing BHK cells. TC N 22A is less active (EC50>10 M) in agonist and PAM model at mGlu 1, 2, 3, 5, and 7 receptors. TC N 22A has the potential for research of CNS disease in vivo. Product information CAS Number: 1314140 00 5 Molecular Weight: 283. 35 Formula: C14H13N5S Chemical Name: (4Z) N (pyridin 2 yl) 5 thia 3,11,12