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THIQ rafenib D3) InChiKey: VEXAKEBSBMAIOB-DHZHZOJOSA-N

SKU: 17113070737

4.7
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Description

InChiKey: VEXAKEBSBMAIOB-DHZHZOJOSA-N

3-[18-(2-carboxyethyl)-8

and provides an antioxidant action either by direct reaction with free radicals or by regeneration of tocopherol and ascorbate from their oxidised state[1]

Ropelle ER

Formula: C19H35N3O5

THIQ rafenib D3) InChiKey: VEXAKEBSBMAIOB-DHZHZOJOSA-NTHIQ is the first selective agonist of the melanocortin 4 receptor (MC4R), with high affinity and potency for hMC4R (IC50=1. 2 nM, EC50=2. 1 nM) and rMC4R (IC50=0. 6 nM, EC50=2. 9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants. Product

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