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93 μM and inhibts microtubule polymerization
The compound was selective versus a panel of greater than 200 additional receptor tyrosine kinase (RTKs)
reduces the number of adherent leukocytes and inhibits mast cell degranulation and cytokine elevation in rats
Smiles: CC1CC2=CC3OCOC=3C(OC)=C2C2=C(OC)C(OC)=C(C=C2CC1(C)O)OC
Smiles: [2H]C([2H])([2H])C(CCC[C@@H](C)[C@H]1CC[C@H]2/C(/CCC[C@@]21C)=C/C=C1/C[C@@H](O)CCC/1=C)C([2H])([2H])[2H]
12S-HHT 1722 93 μM and inhibts microtubule12S HHT (12(S) HHTrE) is an enzymatic product of prostaglandin H2 (PGH2) derived from cyclooxygenase (COX) mediated arachidonic acid metabolism. 12S HHT is an endogenous ligand for BLT2 that fully activates BLT2 in vivo. 12S HHT suppresses UV induced IL 6 synthesis in keratinocytes, exerting an anti inflammatory activity. Product information CAS Number: 54397 84 1 Molecular Weight: 280. 40 Formula: C17H28O3 Chemical Name: (5Z,8E,10E,12S) 12
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