JP83 Catalog No.:M22642-C Smiles: COC1=CC(/C=C/C2C=CC(O)=CC=2)=CC=C1/C=C/C1C=CC(O)=CC=1

Smiles: COC1=CC(/C=C/C2C=CC(O)=CC=2)=CC=C1/C=C/C1C=CC(O)=CC=1

cell death as measured by LDH release (IC50 = 0

109(51):20853-8

with a 45% inhibition of primary tumor growth at 3

InChiKey: GDLMLQJISATCEL-UHFFFAOYSA-M

JP83 Catalog No.:M22642-C Smiles: COC1=CC(/C=C/C2C=CC(O)=CC=2)=CC=C1/C=C/C1C=CC(O)=CC=1IC50: 14 nM for the human recombinant enzyme JP83 is an irreversible fatty acyl amide hydrolase (FAAH) inhibitor. The enzyme fatty acyl amide hydrolase (FAAH) is capable of hydrolyzing anandamide and other esters and amides with long unsaturated acyl chains, which is widely expressed in brain and other tissues. In vitro: JP83 was identified as an irreversible FAAH inhibitor of the carbamate class when it was tested using radiolabeled oleamide as the