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InChiKey: OLEDRJJUXAAJFN-UHFFFAOYSA-N
10(39):318-24
It inhibited the proliferation of several esophageal
Smiles: CC(NC(=O)C1=CC=CC=C1N=CC1=C(O)C=CC2=CC=CC=C21)C1C=CC=CC=1
only when this is elicited by growth promoting agents which activate PKC
BMS-1166-N-piperidine-COOH Catalog No.:M13983-2 InChiKey: OLEDRJJUXAAJFN-UHFFFAOYSA-NBMS 1166 N piperidine COOH, the BMS 1166 based moiety, binds to E3 ligase ligand via a linker to form PROTAC PD 1 PD L1 degrader 1 (HY 131183) to degrade PD 1 PD L1. BMS 1166 is a potent PD 1 PD L1 interaction inhibitor with an IC50 of 1. 4 nM. BMS 1166 antagonizes the inhibitory effect of PD 1 PD L1 immune checkpoint on T cell activation. Product information CAS Number: 2447066 00 2 Molecular Weight: 639. 14 Formula: C37H35ClN2O6 Chemical Name: 1 ({5
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