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InChi: InChI=1S/C13H13BrN2OS/c1-10-3-4-12(11(14)9-10)17-7-8-18-13-15-5-2-6-16-13/h2-6
Microsome metabolism studies and rat pharmacokinetic analysis suggests significantly more rapid metabolism of PG01 than SF-03
GNE-781 modulates MYC expression that corresponds with antitumor activity in an AML tumor model
InChiKey: HCFDWZZGGLSKEP-NPMXJOAUSA-N
InChi: InChI=1S/C20H23NO3S/c1-2-17-18(23-11-10-22-17)13-15(1)14-21-7-5-20(6-8-21)16-4-12-25-19(16)3-9-24-20/h1-2
RRx-001 7464 InChi: InChI=1S/C13H13BrN2OS/c1-10-3-4-12(11(14)9-10)17-7-8-18-13-15-5-2-6-16-13/h2-6RRx 001, a hypoxia selective epigenetic agent and studied as a radio and chem sensitizer, triggers apoptosis and overcomes drug resistance in myeloma. RRx 001 exhibits potent anti tumor activity with minimal toxicity. RRx 001 is a dual small molecule checkpoint inhibitor by downregulating CD47 and SIRP . RRx 001 is a potent inhibitor of G6PD and shows potent antimalarial activity. Product information CAS Number: 925206 65 1 Molecular Weight: 268. 02