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Harashima H
FGFR inhibitor AZD4547 binds to and inhibits FGFR
[(2R)-1-{[4-({3-[(benzenesulfonyl)methyl]-5-methylphenoxy}methyl)phenyl]methyl}pyrrolidin-2-yl]methanol
6%) in the fraction of apoptotic cells as assessed by Annexin V/PI staining
CID-6451149
BMS-564929 0364 Harashima HBMS 564929 is a highly potent, orally active, nonsteroidal tissue selective androgen receptor (AR) modulator. BMS 564929 is a subnanomolar AR agonist in vitro, is highly selective for the AR vs. other steroid hormone receptors, and exhibits no significant interactions with SHBG or aromatase. Dose response studies in castrated male rats show that BMS 564929 is substantially more potent than testosterone (T) in stimulating the growth of the levator ani