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1 μM for FKBP51 and an IC50 of 2
Chemical Name: 4-{[4-(2
Thiol Probes To Detect Electrophilic Natural Products Based on Their Mechanism of Action
InChi: InChI=1S/C16H14FN3O/c1-10-4-2-3-5-14(10)20-15(9-17)19-13-7-6-11(18)8-12(13)16(20)21/h2-8H
Smiles: OC(C1C=CC(=CC=1)NC(=O)C1=CC=CC=C1Cl)(C(F)(F)F)C(F)(F)F
MFZ 10-7 hydrochloride Size:Contact [email protected] for quotation 1 μM for FKBP51 andMFZ 10 7 hydrochloride is a highly potent and selective mGluR5 NAM (negative allosteric modulator), with a Ki of 0. 67 nM for rat mGluR5. MFZ 10 7 hydrochloride inhibits cocaine taking and cocaine seeking behavior in rats. Product information CAS Number: 1779796 36 9 Molecular Weight: 272. 70 Formula: C15H10ClFN2 Chemical Name: 3 fluoro 5 [2 (6 methylpyridin 2 yl)ethynyl]benzonitrile; chlorohydrogen Smiles: Cl. CC1=CC=CC(C#CC2C=C(C=C(F)C=2)C#N)=N1