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ALX-1393 27420 The SB202190 group also shows

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Description

The SB202190 group also shows significantly reduced neuronal apoptosis in the hippocampus compared to VaD model rats (P<0

Ft1 enhanced the phosphorylation of ERK1/2

8-M-PDOT (10 µg/µL

It increases the activity of pSer9-glycogen synthase kinase and insulin degrading enzyme (IDE) and reduces the accumulation of amyloid-β (1-42) (Aβ42) in the rat hippocampal CA1 and CA3 regions in a model of vascular dementia induced by chronic cerebral hypofusion

but it remains unaffected relative to body weight (g/100 g body weight)

ALX-1393 27420 The SB202190 group also showsALX 1393, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model. Product information CAS Number: 949164 09 4 Molecular Weight: 395. 42 Formula: C23H22FNO4 Chemical Name: (2S) 2 amino 3 {[2 (benzyloxy)phenyl](3 fluorophenyl)methoxy}propanoic acid Smiles: N[C@@H](COC(C1=CC=CC=C1OCC1C=CC=CC=1)C1=CC(F)=CC=C1)C(O)=O InChiKey: ADUSZEGHFWRTQS AIBWNMTMSA N InChi: InChI=1S

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