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BMS-378806 Catalog No.:M10727-10 2-bis(4-fluorophenyl)-2-phenylacetamide

SKU: 22695078770

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Description

2-bis(4-fluorophenyl)-2-phenylacetamide

It is in the protease inhibitor class and works by blocking the HIV protease

Formula: C24H38N2O4

Chemical Name: 2-propylpentanoic acid sodium

InChi: InChI=1S/C33H38N4O6/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26

BMS-378806 Catalog No.:M10727-10 2-bis(4-fluorophenyl)-2-phenylacetamideBMS 378806 is a small molecule that inhibits the first step of HIV 1 infection by blocking the binding of host cell CD4 with viral gp120 protein. It binds the exterior envelope glycoprotein gp120 (Kd= 21. 1 nM; Ki = 24. 9 nM), blocking the conformational change that occurs with CD4 binding and preventing fusion of the viral and target cell membranes. Product information CAS Number: 357263 13 9 Molecular Weight: 406. 43 Formula: C22H22N4O4 Chemical

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