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443(3):209-12
InChi: InChI=1S/C33H43N7O2/c1-7-8-24-15-23(6)37-33(42)28(24)19-35-32(41)27-16-26(17-30-29(27)20-36-40(30)22(4)5)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10
but not with RARβ and RXRα
AZT can enhance CRISPR-mediated sequence-specific gene knockout via NHEJ in human induced pluripotent stem cells (iPSCs) and other cell types
PMID: 33017361
Mutant IDH1-IN-2 ecyl sulfate D25 443(3):209-12Mutant IDH1 IN 2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS MS biochemical assay, IC50 of 16. 6 nM in Fluorescence biochemical assay. Target: Mutant IDH1Mutant IDH1 IN 2 has a neomorphic activity and in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell proliferation disorders, such as cancer. More bioactivity information in Patent WO