ICA-105665 Catalog No.:M15782-C also has less inhibition on

also has less inhibition on AChE/BChE with Ki of 48

Epub 2014 Feb 27

(2002) J Neuropathol Exp Neurol

2014:149628

InChiKey: PQFRTXSWDXZRRS-UHFFFAOYSA-N

ICA-105665 Catalog No.:M15782-C also has less inhibition onICA 105665 (PF 04895162) is a potent and orally active neuronal Kv7. 2 7. 3 and Kv7. 3 7. 5 potassium channels opener. ICA 105665 inhibits liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 M). ICA 105665 can penetrate the blood brain barrier and has antiseizure effects. Product information Molecular Weight: 355. 34 Formula: C19H15F2N3O2 Chemical Name: N (2 cyclopropyl 7 fluoro 4 oxo 3,4 dihydroquinazolin 3 yl) 2