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Protein geranylgeranylation is required for osteoclast formation
and completely prevents the decrease of BMC and BMD of DFM induced by ovariectomized (OVX) at 20 mg/kg/day
The induction of cytotoxicity was associated with inhibition of cell cycle progression and induction of apoptosis in myeloma cell lines and patient-derived plasma cells
Formula: C8H4Cl2N2O2
Solubility: DMSO : 250 mg/mL (682
Cariprazine D8 dime pentahydrate Protein geranylgeranylation is required forCariprazine D8 (RGH 188 D8) is a deuterium labeled Cariprazine. Cariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0. 085 nM) and D2 (Ki=0. 49 nM) receptors, and moderate affinity for the 5 HT1A receptor (Ki=2. 6 nM). Product information CAS Number: 1308278 50 3 Molecular Weight: 435. 46 Formula: C21H32Cl2N4O Chemical Name: 3 ((1r, 4r) 4 (2 (4 (2, 3 dichlorophenyl)piperazin 1 yl 2, 2, 3, 3, 5, 5, 6, 6
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