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VTP-27999 TFA - a renin inhibitor. CAS# 1013937-63-7 Size:Solid 10 mg 6-b]pyridine-2

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Description

6-b]pyridine-2

93 mM) Water 48 mg/mL (198

GJ 103 sodium

The inhibitory activity of WZB117 on cancer cell growth is also confirmed with a clonogenic assay

InChi: InChI=1S/C27H28N6O/c1-3-34-21-8-4-18(5-9-21)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-7-20(17-25(23)31-27)33-14-12-32(2)13-15-33/h4-11

VTP-27999 TFA - a renin inhibitor. CAS# 1013937-63-7 Size:Solid 10 mg 6-b]pyridine-2VTP 27999 is a highly potent and selective renin inhibitor (IC50 = 0. 47 nM). VTP 27999 demonstrated excellent selectivity over related and unrelated off targets, >15% oral bioavailability in three species, oral efficacy in a double transgenic rat model of hypertension, and good exposure in humans. Product information CAS Number: 1013937 63 7 Molecular Weight: 639. 10 Formula: C28H42ClF3N4O7 Synonym: VTP 27999, 2, 2, 2 trifluoroacetate VTP27999, 2, 2,

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