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CBP and EP300 are highly homologous
It has binding affinity to the human GPR40 receptor with Ki of 38 nM and the rat GPR40 receptor with Ki of 140 nM
which range from 4 to 58 nM
Phytochem Anal
Mäkinen P
PKC-iota inhibitor 1 - CAS# 2328094-11-5 size:2mg solid CBP and EP300 are highlyPKC iota inhibitor 1, CAS No. 2328094 11 5, is a protein kinase C iota (PKC ) inhibitor with an IC50 value of 0. 34 M. Product information CAS Number: 2328094 11 5 Molecular Weight: 374. 44 Formula: C21H22N6O Chemical Name: 2 amino 5 (3 (piperazin 1 yl)phenyl) N (pyridin 4 yl)nicotinamide Smiles: NC1=NC=C(C=C1C(=O)NC1=CC=NC=C1)C1C=C(C=CC=1)N1CCNCC1 InChiKey: YDMJAALVMGFGRY UHFFFAOYSA N InChi: InChI=1S C21H22N6O c22 20 19(21(28)26 17 4 6 23 7 5 17)13