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WWL113 was administered by oral dosing once a day at a dose of 30-50 mg/kg in the model of diet-induced obesity ordb/db mice
A-484954 is a highly selective eEF2K inhibitor with an IC50 value of 280 nM against eEF2K in the enzymatic assay and little activity against a wide panel of serine/threonine and tyrosine kinases
beta-Me-ATP-evoked depolarizations but did not alter depolarizations evoked by UTP
InChi: InChI=1S/C22H21F2N9O/c23-14-3-4-17(16(24)12-14)31-8-5-30(6-9-31)7-10-32-20-15(13-26-32)21-27-19(18-2-1-11-34-18)29-33(21)22(25)28-20/h1-4
2K/c1-14(2)9-21(33)47-24-23(49-51(42
Trimetazidine-N-oxide Catalog No.:M28034-C WWL113 was administered by oralTrimetazidine N oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long chain 3 ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti oxidant, anti inflammatory, antinociceptive and gastroprotective properties. Product information CAS Number: 1644530 89 1 Molecular Weight: 282. 34 Formula: C14H22N2O4 Chemical Name: 4 [(2,3,4
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