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a IIa trial and a IIb trial of AN-2728 in patients with psoriasis had been completed
PubMed PMID: 23968981
N-dimethylsphingosine (DMS) inhibits both SK1 and SK2 with IC50 values of approximately 60 and 20 μM
CI-1040 inhibits 86% of papillary thyroid carcinoma (PTC) cell growth with the RET/PTC1 rearrangement at 10μM compared with cells treated with DMSO only
OC1=NC=CC2C1=CC=CC=2S(=O)(=O)N1CCCNCC1
DC41 - CAS# 1354787-69-1 el (hydrogen sulfate) a IIa trial and aDC41 is a DC1 derivative. DC1, a simplified analogue of CC 1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer. Product information CAS Number: 1354787 69 1 Molecular Weight: 680. 21 Formula: C37H34ClN5O4S Chemical Name: N {2 [(1S) 1 (chloromethyl) 5 hydroxy 1H, 2H, 3H benzo[e]indole 3 carbonyl] 1H indol 5 yl} 5 (4 methyl 4 sulfanylpentanamido) 1H indole 2 carboxamide Smiles:
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