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Advances in Functional Materials 18(13)
which is a third-generation EGFR inhibitor
3-dihydro-1H-inden- 1-yl]-1
InChi: InChI=1S/C9H4Cl2O2S/c10-4-1-2-5-6(3-4)14-8(7(5)11)9(12)13/h1-3H
EMAC10101d is a potent and selective inhibitor of Carbonic Anhydrase Isoform toward hCA II with an inhibitory activity in the low nanomolar range
D-α-Hydroxyglutaric acid odesine Advances in Functional Materials 18(13)D Hydroxyglutaric acid ((R) 2 Hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D 2 hydroxyglutaric aciduria. D Hydroxyglutaric acid is a weak competitive antagonist of ketoglutarate ( KG) and inhibits multiple KG dependent dioxygenases with a Ki of 10. 87 mM. D Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling.