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CCT 251545
31)32/h3-12
The affinity of Eptapirone (F11440) for 5-HT1Abinding sites (pKi
Anacetrapib decreases pre-β-HDL formation by more than 46% (P<0
long elimination half-live and efficacy in animal models
Gemcitabine - CAS# 95058-81-4 otecan hydrochloride trihydrate CCT 251545Gemcitabine is an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Product information CAS