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40(6):3071-3080
INCB-3284 is a potent
CAS Number: 1911564-39-0
Epub 2018 Apr 25
187:111952
CMLD-2 - CAS# 958843-91-9 Demethylase 40(6):3071-3080CMLD 2, an inhibitor of HuR ARE interaction, competitively binds HuR protein disrupting its interaction with adenine uridine rich elements (ARE) containing mRNAs (Ki=350 nM). CMLD 2 induces apoptosis exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Hu antigen R (HuR) is an RNA binding protein, can regulate target mRNAs stability and translation. Product information CAS Number: 958843 91 9
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